7TXB

Structure of the Class II Fructose-1,6-Bisphophatase from Mycobacterium tuberculosis complexed with substrate F1,6BP

7TXB の概要

• エントリーDOI: 10.2210/pdb7txb/pdb
• 分子名称: Fructose-1,6-bisphosphatase class 2, GLYCEROL, 1,6-di-O-phosphono-beta-D-fructofuranose, ... (5 entities in total)
• 機能のキーワード: class ii fbpases; fructose-1, 6-bisphosphatase; francisella tularensis; mycobacterium tuberculosis; gluconeogenesis; antibiotic targets, hydrolase, hydrolase-substrate complex, hydrolase/substrate
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74233.89

構造登録者

Abad-Zapatero, C.,Selezneva, A.I.,Gutka, H.J. (登録日: 2022-02-08, 公開日: 2023-06-28, 最終更新日: 2023-10-25)

• 主引用文献: Selezneva, A.I.,Harding, L.N.M.,Gutka, H.J.,Movahedzadeh, F.,Abad-Zapatero, C.; New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class.; Plos One, 18:e0274723-e0274723, 2023; PubMed: 37352301; DOI: 10.1371/journal.pone.0274723

実験手法

X-RAY DIFFRACTION (3.71 Å)