7TXA

Structure of the Class II Fructose-1,6-Bisphophatase from Francisella tularensis complexed with native metal cofactor Mn++ and product F6P

7TXA の概要

• エントリーDOI: 10.2210/pdb7txa/pdb
• 分子名称: Fructose-1,6-bisphosphatase, MANGANESE (II) ION, 6-O-phosphono-beta-D-fructofuranose, ... (4 entities in total)
• 機能のキーワード: class ii fbpases; fructose-1, 6-bisphosphatase; francisella tularensis; mycobacterium tuberculosis; gluconeogenesis; antibiotic targets, hydrolase, hydrolase-product complex, hydrolase/product
• 由来する生物種: Francisella tularensis
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 297349.09

構造登録者

Abad-Zapatero, C.,Selezneva, A.I. (登録日: 2022-02-08, 公開日: 2023-06-28, 最終更新日: 2023-10-25)

• 主引用文献: Selezneva, A.I.,Harding, L.N.M.,Gutka, H.J.,Movahedzadeh, F.,Abad-Zapatero, C.; New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class.; Plos One, 18:e0274723-e0274723, 2023; PubMed: 37352301; DOI: 10.1371/journal.pone.0274723

実験手法

X-RAY DIFFRACTION (2.4 Å)