7TX5

Neutron crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ADP-ribose at 293 K (C2 crystal form)

7TX5 の概要

• エントリーDOI: 10.2210/pdb7tx5/pdb
• 分子名称: Papain-like protease nsp3, ADENOSINE-5-DIPHOSPHORIBOSE (3 entities in total)
• 機能のキーワード: sars-cov-2, room temperature diffraction, protein dynamics, water networks, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18778.04

構造登録者

Correy, G.J.,Fraser, J.S.,Kovalevsky, A. (登録日: 2022-02-07, 公開日: 2022-02-23, 最終更新日: 2023-10-25)

• 主引用文献: Correy, G.J.,Kneller, D.W.,Phillips, G.,Pant, S.,Russi, S.,Cohen, A.E.,Meigs, G.,Holton, J.M.,Gahbauer, S.,Thompson, M.C.,Ashworth, A.,Coates, L.,Kovalevsky, A.,Meilleur, F.,Fraser, J.S.; The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature.; Sci Adv, 8:eabo5083-eabo5083, 2022; PubMed: 35622909; DOI: 10.1126/sciadv.abo5083

実験手法

NEUTRON DIFFRACTION (2.3 Å)
X-RAY DIFFRACTION (1.95 Å)