7TVS

The Crystal Structure of SARS-CoV-2 Omicron Mpro (P132H) in complex with demethylated analog of masitinib

7TVS の概要

• エントリーDOI: 10.2210/pdb7tvs/pdb
• 分子名称: 3C-like proteinase nsp5, N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(piperazin-1-yl)methyl]benzamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, omicron, 3cl, masitinib, structural genomics, center for structural genomics of infectious diseases, csgid, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34507.46

構造登録者

Tan, K.,Maltseva, N.I.,Endres, M.J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2022-02-05, 公開日: 2022-02-16, 最終更新日: 2023-10-18)

• 主引用文献: Tan, K.,Maltseva, N.I.,Endres, M.J.,Joachimiak, A.; The Crystal Structure of SARS-CoV-2 Omicron Mpro (P132H) in complex with demethylated analog of masitinib; To Be Published,

実験手法

X-RAY DIFFRACTION (1.88612877612 Å)