7TTX
Crystal structure of potent neutralizing antibody 10-40 in complex with Sarbecovirus bat RaTG13 receptor-binding domain
7TTX の概要
エントリーDOI | 10.2210/pdb7ttx/pdb |
分子名称 | Spike glycoprotein, 1040 heavy chain, 1040 light chain, ... (4 entities in total) |
機能のキーワード | covid-19, sarbecovirus, ratg13 rbd, viral protein, spike glycoprotein, receptor binding protein, neutralizing antibody, potent, 10-40, fab, viral protein-immune system complex, viral protein/immune system |
由来する生物種 | Bat coronavirus RaTG13 詳細 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 75028.57 |
構造登録者 | |
主引用文献 | Liu, L.,Iketani, S.,Guo, Y.,Reddem, E.R.,Casner, R.G.,Nair, M.S.,Yu, J.,Chan, J.F.,Wang, M.,Cerutti, G.,Li, Z.,Morano, N.C.,Castagna, C.D.,Corredor, L.,Chu, H.,Yuan, S.,Poon, V.K.,Chan, C.C.,Chen, Z.,Luo, Y.,Cunningham, M.,Chavez, A.,Yin, M.T.,Perlin, D.S.,Tsuji, M.,Yuen, K.Y.,Kwong, P.D.,Sheng, Z.,Huang, Y.,Shapiro, L.,Ho, D.D. An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14:eabn6859-eabn6859, 2022 Cited by PubMed: 35438546DOI: 10.1126/scitranslmed.abn6859 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.8 Å) |
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