7TQP
Structure of human TREX1
Summary for 7TQP
Entry DOI | 10.2210/pdb7tqp/pdb |
Descriptor | Three-prime repair exonuclease 1, SULFATE ION (3 entities in total) |
Functional Keywords | nuclease, dnase, innate immunity, autoimmunity, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 26665.39 |
Authors | Zhou, W.,Richmond-Buccola, D.,Kranzusch, P.J. (deposition date: 2022-01-26, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Zhou, W.,Richmond-Buccola, D.,Wang, Q.,Kranzusch, P.J. Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13:4277-4277, 2022 Cited by PubMed: 35879334DOI: 10.1038/s41467-022-32055-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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