7TQG

Crystal Structure of IOMA Fab inferred germline

Summary for 7TQG

• Entry DOI: 10.2210/pdb7tqg/pdb
• Descriptor: IOMA iGL Fab Heavy Chain, IOMA iGL Fab Light Chain (2 entities in total)
• Functional Keywords: hiv, antibody, antiviral protein, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 46297.60

Authors

Gristick, H.B.,Bjorkman, P.J. (deposition date: 2022-01-26, release date: 2023-03-01, Last modification date: 2023-10-25)

• Primary citation: Gristick, H.B.,Hartweger, H.,Loewe, M.,van Schooten, J.,Ramos, V.,Oliveira, T.Y.,Nishimura, Y.,Koranda, N.S.,Wall, A.,Yao, K.H.,Poston, D.,Gazumyan, A.,Wiatr, M.,Horning, M.,Keeffe, J.R.,Hoffmann, M.A.G.,Yang, Z.,Abernathy, M.E.,Dam, K.A.,Gao, H.,Gnanapragasam, P.N.P.,Kakutani, L.M.,Pavlovitch-Bedzyk, A.J.,Seaman, M.S.,Howarth, M.,McGuire, A.T.,Stamatatos, L.,Martin, M.A.,West Jr., A.P.,Nussenzweig, M.C.,Bjorkman, P.J.; CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.; Sci Immunol, 8:eade6364-eade6364, 2023; PubMed: 36763635; DOI: 10.1126/sciimmunol.ade6364

Experimental method

X-RAY DIFFRACTION (2.07 Å)