7TQB

Crystal structure of monoclonal S9.6 Fab bound to DNA-RNA hybrid

Summary for 7TQB

Entry DOI	10.2210/pdb7tqb/pdb
Descriptor	FAB S9.6 Heavy Chain, FAB S9.6 Light Chain, RNA, ... (6 entities in total)
Functional Keywords	antibody fab dna:rna hybrid nucleic acid dna:rna hybrid binding protein, dna-rna hybrid, immune system-dna-rna hybrid complex, immune system/dna-rna hybrid
Biological source	synthetic construct More
Total number of polymer chains	4
Total formula weight	57284.80
Authors	Bou-Nader, C.,Zhang, J. (deposition date: 2022-01-26, release date: 2022-03-30, Last modification date: 2023-11-15)
Primary citation	Bou-Nader, C.,Bothra, A.,Garboczi, D.N.,Leppla, S.H.,Zhang, J. Structural basis of R-loop recognition by the S9.6 monoclonal antibody. Nat Commun, 13:1641-1641, 2022 Cited by PubMed: 35347133 DOI: 10.1038/s41467-022-29187-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation