7TOQ
Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein poly-PR
This is a non-PDB format compatible entry.
Summary for 7TOQ
Entry DOI | 10.2210/pdb7toq/pdb |
EMDB information | 26035 |
Descriptor | 18S rRNA, uL30, eL8, ... (85 entities in total) |
Functional Keywords | ribosomal binding peptide, als/ftd-associated dipeptide repeat protein, ribosome |
Biological source | Oryctolagus cuniculus (rabbit) More |
Total number of polymer chains | 84 |
Total formula weight | 3177725.45 |
Authors | Loveland, A.B.,Svidritskiy, E.,Susorov, D.,Lee, S.,Park, A.,Zvornicanin, S.,Demo, G.,Gao, F.B.,Korostelev, A.A. (deposition date: 2022-01-24, release date: 2022-05-25, Last modification date: 2024-02-21) |
Primary citation | Loveland, A.B.,Svidritskiy, E.,Susorov, D.,Lee, S.,Park, A.,Zvornicanin, S.,Demo, G.,Gao, F.B.,Korostelev, A.A. Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13:2776-2776, 2022 Cited by PubMed: 35589706DOI: 10.1038/s41467-022-30418-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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