7TMC

TMEM106B singlet filament extracted from MSTD neurodegenerative human brain

Summary for 7TMC

Entry DOI	10.2210/pdb7tmc/pdb
EMDB information	25995
Descriptor	Transmembrane protein 106B, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	tmem106b, tmem filament, mstd, neuropeptide
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	96123.45
Authors	Hoq, M.R.,Bharath, S.R.,Jiang, W. (deposition date: 2022-01-19, release date: 2023-01-25, Last modification date: 2024-10-30)
Primary citation	Hoq, M.R.,Bharath, S.R.,Hallinan, G.I.,Fernandez, A.,Vago, F.S.,Ozcan, K.A.,Li, D.,Garringer, H.J.,Vidal, R.,Ghetti, B.,Jiang, W. Cross-beta helical filaments of Tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia. Acta Neuropathol, 145:707-710, 2023 Cited by PubMed: 36952000 DOI: 10.1007/s00401-023-02563-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.25 Å)

Structure validation