7TKT

SthK closed state, cAMP-bound in the presence of detergent

Summary for 7TKT

Entry DOI	10.2210/pdb7tkt/pdb
EMDB information	25916 25917 25981
Descriptor	Putative transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (3 entities in total)
Functional Keywords	cyclic nucleotide-gated channel, lipid modulation, pacemaker channel, transport protein
Biological source	Spirochaeta thermophila DSM 6578
Total number of polymer chains	4
Total formula weight	244739.48
Authors	Rheinberger, J.,Schmidpeter, P.A.,Nimigean, C.M. (deposition date: 2022-01-17, release date: 2022-10-26, Last modification date: 2024-06-05)
Primary citation	Schmidpeter, P.A.M.,Wu, D.,Rheinberger, J.,Riegelhaupt, P.M.,Tang, H.,Robinson, C.V.,Nimigean, C.M. Anionic lipids unlock the gates of select ion channels in the pacemaker family. Nat.Struct.Mol.Biol., 29:1092-1100, 2022 Cited by PubMed: 36352139 DOI: 10.1038/s41594-022-00851-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation