7TJ5

SthK closed state, cAMP-bound in the presence of POPA

Summary for 7TJ5

• Entry DOI: 10.2210/pdb7tj5/pdb
• EMDB information: 25916 25917 25981
• Descriptor: Putative transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate (3 entities in total)
• Functional Keywords: cyclic nucleotide-gated channel, lipid modulation, pacemaker channel, transport protein
• Biological source: Spirochaeta thermophila DSM 6578
• Total number of polymer chains: 4
• Total formula weight: 224689.13

Authors

Schmidpeter, P.A.,Nimigean, C.M. (deposition date: 2022-01-14, release date: 2022-10-26, Last modification date: 2024-06-05)

• Primary citation: Schmidpeter, P.A.M.,Wu, D.,Rheinberger, J.,Riegelhaupt, P.M.,Tang, H.,Robinson, C.V.,Nimigean, C.M.; Anionic lipids unlock the gates of select ion channels in the pacemaker family.; Nat.Struct.Mol.Biol., 29:1092-1100, 2022; PubMed: 36352139; DOI: 10.1038/s41594-022-00851-2

Experimental method

ELECTRON MICROSCOPY (2.41 Å)