7TDM

CryoEM Structure of sFab COP-2 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain

7TDM の概要

• エントリーDOI: 10.2210/pdb7tdm/pdb
• EMDBエントリー: 25834
• 分子名称: Claudin-4, Heat-labile enterotoxin B chain, COP-2 Fab Heavy chain, ... (4 entities in total)
• 機能のキーワード: claudin, cell adhesion, enterotoxin, fab, antibody fragment, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 85985.21

構造登録者

Vecchio, A.J. (登録日: 2022-01-01, 公開日: 2022-02-09, 最終更新日: 2024-01-17)

• 主引用文献: Orlando, B.J.,Dominik, P.K.,Roy, S.,Ogbu, C.P.,Erramilli, S.K.,Kossiakoff, A.A.,Vecchio, A.J.; Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.; J.Biol.Chem., 298:102357-102357, 2022; PubMed: 35952760; DOI: 10.1016/j.jbc.2022.102357

実験手法