7TBY

The structure of human ABCA1 in nanodisc

7TBY の概要

• エントリーDOI: 10.2210/pdb7tby/pdb
• EMDBエントリー: 25800 25801 25802 25803
• 分子名称: ATP-binding cassette, sub-family A (ABC1), member 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: hdl, cholesterol, tangier disease, abc transporter, transport protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 257819.28

構造登録者

Sun, Y.,Li, X. (登録日: 2021-12-22, 公開日: 2022-01-26, 最終更新日: 2023-05-24)

• 主引用文献: Sun, Y.,Li, X.; Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.; Nat Cardiovasc Res, 1:238-245, 2022; PubMed: 37181814; DOI: 10.1038/s44161-022-00022-y

実験手法

ELECTRON MICROSCOPY (4 Å)