7TBV

Crystal structure of the shikimate kinase + 3-dehydroquinate dehydratase + 3-dehydroshikimate dehydrogenase domains of Aro1 from Candida albicans

Summary for 7TBV

Entry DOI	10.2210/pdb7tbv/pdb
Descriptor	Pentafunctional AROM polypeptide, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	chorismate biosynthesis, structural genomics, center for structural genomics of infectious diseases, csgid, transferase, oxidoreductase
Biological source	Candida albicans Ca6
Total number of polymer chains	4
Total formula weight	311286.50
Authors	Stogios, P.J.,Evdokimova, E.,Michalska, K.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-12-22, release date: 2022-03-16, Last modification date: 2023-10-25)
Primary citation	Stogios, P.J.,Liston, S.D.,Semper, C.,Quade, B.,Michalska, K.,Evdokimova, E.,Ram, S.,Otwinowski, Z.,Borek, D.,Cowen, L.E.,Savchenko, A. Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5:-, 2022 Cited by PubMed: 35512834 DOI: 10.26508/lsa.202101358 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation