7TBA
Pentraxin - ligand complex
Summary for 7TBA
Entry DOI | 10.2210/pdb7tba/pdb |
Descriptor | C-reactive protein, [3-(dibutylamino)propyl]phosphonic acid, CALCIUM ION (3 entities in total) |
Functional Keywords | inflammation, inhibitor, complex, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 20 |
Total formula weight | 467989.96 |
Authors | Shing, K.S.C.T.,Morton, C.J.,Parker, M.W. (deposition date: 2021-12-21, release date: 2022-10-19, Last modification date: 2023-10-25) |
Primary citation | Zeller, J.,Cheung Tung Shing, K.S.,Nero, T.L.,McFadyen, J.D.,Krippner, G.,Bogner, B.,Kreuzaler, S.,Kiefer, J.,Horner, V.K.,Braig, D.,Danish, H.,Baratchi, S.,Fricke, M.,Wang, X.,Kather, M.G.,Kammerer, B.,Woollard, K.J.,Sharma, P.,Morton, C.J.,Pietersz, G.,Parker, M.W.,Peter, K.,Eisenhardt, S.U. A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein. Embo Mol Med, 15:e16236-e16236, 2023 Cited by PubMed: 36468184DOI: 10.15252/emmm.202216236 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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