7TB4

Cryo-EM structure of the spike of SARS-CoV-2 Omicron variant of concern

7TB4 の概要

• エントリーDOI: 10.2210/pdb7tb4/pdb
• EMDBエントリー: 25792
• 分子名称: Surface glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: sars-cov-2, spike, omicron, variant of concern, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 410176.33

構造登録者

Zhou, T.,Tsybovsky, T.,Kwong, P.D. (登録日: 2021-12-21, 公開日: 2022-01-12, 最終更新日: 2022-01-19)

• 主引用文献: Wang, L.,Zhou, T.,Zhang, Y.,Yang, E.S.,Schramm, C.A.,Shi, W.,Pegu, A.,Oloninyi, O.K.,Ransier, A.,Darko, S.,Narpala, S.R.,Hatcher, C.,Martinez, D.R.,Tsybovsky, Y.,Phung, E.,Abiona, O.M.,Cale, E.M.,Chang, L.A.,Corbett, K.S.,DiPiazza, A.T.,Gordon, I.J.,Leung, K.,Liu, T.,Mason, R.D.,Nazzari, A.,Novik, L.,Olia, A.S.,Doria-Rose, N.A.,Stephens, T.,Stringham, C.D.,Talana, C.A.,Teng, I.T.,Wagner, D.,Widge, A.T.,Zhang, B.,Roederer, M.,Ledgerwood, J.E.,Ruckwardt, T.J.,Gaudinski, M.R.,Baric, R.S.,Graham, B.S.,McDermott, A.B.,Douek, D.C.,Kwong, P.D.,Mascola, J.R.,Sullivan, N.J.,Misasi, J.; Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants.; Biorxiv, 2021; PubMed: 33655252; DOI: 10.1101/2021.02.25.432969

実験手法

ELECTRON MICROSCOPY (3.29 Å)