7TAZ

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor

7TAZ の概要

• エントリーDOI: 10.2210/pdb7taz/pdb
• 分子名称: Reverse transcriptase/ribonuclease H, Reverse transcriptase p51, 2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, ... (4 entities in total)
• 機能のキーワード: reverse transcriptase, hiv-1, polymerase, nnrti, vm-1500, elsulfavirine, viral protein, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114659.00

構造登録者

Snyder, A.A.,Risener, C.J.,Kirby, K.A.,Sarafianos, S.G. (登録日: 2021-12-21, 公開日: 2023-04-12, 最終更新日: 2023-10-25)

• 主引用文献: Snyder, A.A.,Risener, C.J.,Kirby, K.A.,Stefan, S.G.; Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)