7T7C

The hexagonal organization of Munc13-1 C1-C2B-MUN-C2C domains between lipid bilayers

This is a non-PDB format compatible entry.

Summary for 7T7C

• Entry DOI: 10.2210/pdb7t7c/pdb
• EMDB information: 25737
• Descriptor: Protein unc-13 homolog A Chimera (1 entity in total)
• Functional Keywords: synaptic transmission, munc13, membrane fusion, exocytosis
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 12
• Total formula weight: 1570750.40

Authors

Grushin, K.,Sindelar, C.V. (deposition date: 2021-12-15, release date: 2022-02-09, Last modification date: 2024-02-28)

• Primary citation: Grushin, K.,Kalyana Sundaram, R.V.,Sindelar, C.V.,Rothman, J.E.; Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.; Proc.Natl.Acad.Sci.USA, 119:-, 2022; PubMed: 35135883; DOI: 10.1073/pnas.2121259119

Experimental method

ELECTRON MICROSCOPY (10 Å)