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7T7B

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab

Summary for 7T7B
Entry DOI10.2210/pdb7t7b/pdb
DescriptorSpike protein S1, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ... (5 entities in total)
Functional Keywordscross-neutralizing antibody; yydrxg; sars-cov-2; adi-62113; sarbecovirus; pattern search; ighd3-22, immune system, immune system-viral protein complex, immune system/viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
More
Total number of polymer chains3
Total formula weight72163.34
Authors
Liu, H.,Wilson, I.A. (deposition date: 2021-12-14, release date: 2022-08-03, Last modification date: 2023-10-18)
Primary citationLiu, H.,Kaku, C.I.,Song, G.,Yuan, M.,Andrabi, R.,Burton, D.R.,Walker, L.M.,Wilson, I.A.
Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron.
Commun Biol, 5:766-766, 2022
Cited by
PubMed: 35906394
DOI: 10.1038/s42003-022-03700-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.59 Å)
Structure validation

221051

數據於2024-06-12公開中

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