7T7B

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab

7T7B の概要

• エントリーDOI: 10.2210/pdb7t7b/pdb
• 分子名称: Spike protein S1, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ... (5 entities in total)
• 機能のキーワード: cross-neutralizing antibody; yydrxg; sars-cov-2; adi-62113; sarbecovirus; pattern search; ighd3-22, immune system, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 72163.34

構造登録者

Liu, H.,Wilson, I.A. (登録日: 2021-12-14, 公開日: 2022-08-03, 最終更新日: 2023-10-18)

• 主引用文献: Liu, H.,Kaku, C.I.,Song, G.,Yuan, M.,Andrabi, R.,Burton, D.R.,Walker, L.M.,Wilson, I.A.; Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron.; Commun Biol, 5:766-766, 2022; PubMed: 35906394; DOI: 10.1038/s42003-022-03700-6

実験手法

X-RAY DIFFRACTION (2.59 Å)