7T6M
Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1
Summary for 7T6M
Entry DOI | 10.2210/pdb7t6m/pdb |
EMDB information | 25716 25717 25718 25719 25720 25721 25722 25723 25724 25725 |
Descriptor | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (2 entities in total) |
Functional Keywords | calcium, ion channel, kidney, transport protein |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 4 |
Total formula weight | 338124.61 |
Authors | Fluck, E.C.,Yazici, A.T.,Rohacs, T.,Moiseenkova-Bell, V.Y. (deposition date: 2021-12-14, release date: 2022-05-04, Last modification date: 2024-02-28) |
Primary citation | Fluck, E.C.,Yazici, A.T.,Rohacs, T.,Moiseenkova-Bell, V.Y. Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39:110737-110737, 2022 Cited by PubMed: 35476976DOI: 10.1016/j.celrep.2022.110737 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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