7T68
Co-crystal structure of Chaetomium glucosidase with compound UV-5
This is a non-PDB format compatible entry.
Summary for 7T68
Entry DOI | 10.2210/pdb7t68/pdb |
Descriptor | Chaetomium alpha glucosidase, (2R,3R,4R,5S)-1-[6-(4-azido-2-nitroanilino)hexyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, GLYCEROL, ... (7 entities in total) |
Functional Keywords | alpha glucosidase i, hydrolase, inhibitor complex, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Chaetomium thermophilum var. thermophilum DSM 1495 |
Total number of polymer chains | 2 |
Total formula weight | 189351.98 |
Authors | Karade, S.S.,Mariuzza, R.A. (deposition date: 2021-12-13, release date: 2022-05-04, Last modification date: 2023-10-18) |
Primary citation | Karade, S.S.,Kolesnikov, A.,Treston, A.M.,Mariuzza, R.A. Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design. Biochemistry, 61:822-832, 2022 Cited by PubMed: 35476408DOI: 10.1021/acs.biochem.2c00092 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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