7T4G

The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11

7T4G の概要

• エントリーDOI: 10.2210/pdb7t4g/pdb
• EMDBエントリー: 25676
• 分子名称: Envelope glycoprotein gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• 機能のキーワード: siv, env, vaccine, neutralizing antibody, glycoprotein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Simian immunodeficiency virus; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 505372.60

構造登録者

Berndsen, Z.T.,Ward, A.B. (登録日: 2021-12-09, 公開日: 2022-10-19, 最終更新日: 2023-07-05)

• 主引用文献: Zhao, F.,Berndsen, Z.T.,Pedreno-Lopez, N.,Burns, A.,Allen, J.D.,Barman, S.,Lee, W.H.,Chakraborty, S.,Gnanakaran, S.,Sewall, L.M.,Ozorowski, G.,Limbo, O.,Song, G.,Yong, P.,Callaghan, S.,Coppola, J.,Weisgrau, K.L.,Lifson, J.D.,Nedellec, R.,Voigt, T.B.,Laurino, F.,Louw, J.,Rosen, B.C.,Ricciardi, M.,Crispin, M.,Desrosiers, R.C.,Rakasz, E.G.,Watkins, D.I.,Andrabi, R.,Ward, A.B.,Burton, D.R.,Sok, D.; Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.; Nat Commun, 13:5236-5236, 2022; PubMed: 36068229; DOI: 10.1038/s41467-022-32783-2

実験手法

ELECTRON MICROSCOPY (3.7 Å)