7T3R

IP3 and ATP bound type 3 IP3 receptor in the pre-active C state

This is a non-PDB format compatible entry.

Summary for 7T3R

• Entry DOI: 10.2210/pdb7t3r/pdb
• Related: 7T3P 7T3Q
• EMDB information: 25669
• Descriptor: Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: ip3 receptor, calcium signaling, metal transport
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 1201274.24

Authors

Schmitz, E.A.,Takahashi, H.,Karakas, E. (deposition date: 2021-12-08, release date: 2022-03-23, Last modification date: 2022-05-04)

• Primary citation: Schmitz, E.A.,Takahashi, H.,Karakas, E.; Structural basis for activation and gating of IP 3 receptors.; Nat Commun, 13:1408-1408, 2022; PubMed: 35301323; DOI: 10.1038/s41467-022-29073-2

Experimental method

ELECTRON MICROSCOPY (3.4 Å)