7SYH
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 2(delta dII)
Summary for 7SYH
Entry DOI | 10.2210/pdb7syh/pdb |
EMDB information | 25528 |
Descriptor | 18S rRNA, eS8, uS4, ... (37 entities in total) |
Functional Keywords | hcv, ires, 40s, ribosome |
Biological source | Hepatitis C virus (isolate 1) More |
Total number of polymer chains | 36 |
Total formula weight | 1389783.22 |
Authors | Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. (deposition date: 2021-11-25, release date: 2022-07-13) |
Primary citation | Brown, Z.P.,Abaeva, I.S.,De, S.,Hellen, C.U.T.,Pestova, T.V.,Frank, J. Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published, |
Experimental method | ELECTRON MICROSCOPY (4.6 Å) |
Structure validation
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