7SXP
G-quadruplex structure formed in the NRAS mRNA with a G8U substitution
Summary for 7SXP
Entry DOI | 10.2210/pdb7sxp/pdb |
Descriptor | NRAS mRNA, POTASSIUM ION, CACODYLIC ACID (3 entities in total) |
Functional Keywords | g-quadruplex, nras, rna |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 7635.61 |
Authors | Banco, M.T.,Ferre-D'Amare, A.R. (deposition date: 2021-11-24, release date: 2023-05-31, Last modification date: 2024-05-22) |
Primary citation | Balaratnam, S.,Torrey, Z.R.,Calabrese, D.R.,Banco, M.T.,Yazdani, K.,Liang, X.,Fullenkamp, C.R.,Seshadri, S.,Holewinski, R.J.,Andresson, T.,Ferre-D'Amare, A.R.,Incarnato, D.,Schneekloth Jr., J.S. Investigating the NRAS 5' UTR as a target for small molecules. Cell Chem Biol, 30:643-657.e8, 2023 Cited by PubMed: 37257453DOI: 10.1016/j.chembiol.2023.05.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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