7SWQ

Cryo-EM structure of Arabidopsis Ago10-guide-target RNA complex in a bent duplex conformation

Summary for 7SWQ

• Entry DOI: 10.2210/pdb7swq/pdb
• EMDB information: 25446 25472 25482
• Descriptor: Protein argonaute 10, RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3'), RNA (5'-R(P*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ... (4 entities in total)
• Functional Keywords: mirna, sirna, rna silencing, argonaute, plant, gene regulation
• Biological source: Arabidopsis thaliana (thale cress); More
• Total number of polymer chains: 3
• Total formula weight: 123430.38

Authors

Xiao, Y.,MacRae, I.J. (deposition date: 2021-11-21, release date: 2022-11-23, Last modification date: 2024-06-05)

• Primary citation: Xiao, Y.,Maeda, S.,Otomo, T.,MacRae, I.J.; Structural basis for RNA slicing by a plant Argonaute.; Nat.Struct.Mol.Biol., 30:778-784, 2023; PubMed: 37127820; DOI: 10.1038/s41594-023-00989-7

Experimental method

ELECTRON MICROSCOPY (3.79 Å)