7SQW

Structure of the KcsA-W67F mutant with the activation gate in the closed conformation

Summary for 7SQW

• Entry DOI: 10.2210/pdb7sqw/pdb
• Descriptor: Antibody Fragment, KcsA potassium channel, NONAN-1-OL, ... (6 entities in total)
• Functional Keywords: channel, fab complex, c-type inactivation, membrane protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 58569.10

Authors

Cuello, L.G.,Labro, A.J. (deposition date: 2021-11-07, release date: 2022-10-12, Last modification date: 2023-10-18)

• Primary citation: Coonen, L.,Martinez-Morales, E.,Van De Sande, D.V.,Snyders, D.J.,Cortes, D.M.,Cuello, L.G.,Labro, A.J.; The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels.; Sci Adv, 8:eabn1731-eabn1731, 2022; PubMed: 36112676; DOI: 10.1126/sciadv.abn1731

Experimental method

X-RAY DIFFRACTION (3.21 Å)