7SMT

Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine and carbachol

7SMT の概要

• エントリーDOI: 10.2210/pdb7smt/pdb
• EMDBエントリー: 25202 25205 25206 25207 25208
• 分子名称: Acetylcholine receptor subunit alpha, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• 機能のキーワード: acetylcholine receptor, nicotinic receptor, torpedo, cys-loop receptor, ion channel, muscle-type nicotinic receptor, transport protein
• 由来する生物種: Tetronarce californica (Pacific electric ray); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 278061.86

構造登録者

Rahman, M.M.,Basta, T.,Teng, J.,Lee, M.,Worrell, B.T.,Stowell, M.H.B.,Hibbs, R.E. (登録日: 2021-10-26, 公開日: 2022-03-09, 最終更新日: 2022-04-27)

• 主引用文献: Rahman, M.M.,Basta, T.,Teng, J.,Lee, M.,Worrell, B.T.,Stowell, M.H.B.,Hibbs, R.E.; Structural mechanism of muscle nicotinic receptor desensitization and block by curare.; Nat.Struct.Mol.Biol., 29:386-394, 2022; PubMed: 35301478; DOI: 10.1038/s41594-022-00737-3

実験手法

ELECTRON MICROSCOPY (2.56 Å)