7SLT
Protease inhibitors variant, CTI-homolog pacifastin
Summary for 7SLT
Entry DOI | 10.2210/pdb7slt/pdb |
Descriptor | Protease inhibitor LCMI-II, GLYCEROL (3 entities in total) |
Functional Keywords | cdp, pacifastin, cti, toxin |
Biological source | Locusta migratoria (Migratory locust) |
Total number of polymer chains | 4 |
Total formula weight | 14956.64 |
Authors | Gewe, M.M.,Strong, R.K. (deposition date: 2021-10-24, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Crook, Z.R.,Girard, E.J.,Sevilla, G.P.,Brusniak, M.Y.,Rupert, P.B.,Friend, D.J.,Gewe, M.M.,Clarke, M.,Lin, I.,Ruff, R.,Pakiam, F.,Phi, T.D.,Bandaranayake, A.,Correnti, C.E.,Mhyre, A.J.,Nairn, N.W.,Strong, R.K.,Olson, J.M. Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14:eabn0402-eabn0402, 2022 Cited by PubMed: 35584229DOI: 10.1126/scitranslmed.abn0402 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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