7SKM

Complex between S. aureus aureolysin and wt IMPI.

Summary for 7SKM

• Entry DOI: 10.2210/pdb7skm/pdb
• Related: 7SKL
• Descriptor: Zinc metalloproteinase aureolysin, IMPI alpha, CALCIUM ION, ... (8 entities in total)
• Functional Keywords: metallopeptidase, inhibitor complex, point mutant, hydrolase
• Biological source: Galleria mellonella (Greater wax moth); More
• Total number of polymer chains: 6
• Total formula weight: 83385.50

Authors

Mendes, S.R.,Eckhard, U.,Rodriguez-Banqueri, A.,Guevara, T.,Gomis-Ruth, F.X. (deposition date: 2021-10-21, release date: 2022-01-26, Last modification date: 2023-10-18)

• Primary citation: Mendes, S.R.,Eckhard, U.,Rodriguez-Banqueri, A.,Guevara, T.,Czermak, P.,Marcos, E.,Vilcinskas, A.; An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin; Comput Struct Biotechnol J, 20:534-544, 2022; DOI: 10.1016/j.csbj.2022.01.001

Experimental method

X-RAY DIFFRACTION (1.85 Å)