7SKI

Pertussis toxin in complex with PJ34

7SKI の概要

• エントリーDOI: 10.2210/pdb7ski/pdb
• 分子名称: Pertussis toxin subunit 1, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE (3 entities in total)
• 機能のキーワード: toxin, adp-ribosyltransferase, transferase, whooping cough, inhibitor, pertussis, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Bordetella pertussis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41412.60

構造登録者

Littler, D.R.,Beddoe, T.,Pulliainen, A.,Rossjohn, J. (登録日: 2021-10-20, 公開日: 2022-04-13, 最終更新日: 2023-10-18)

• 主引用文献: Sakari, M.,Tran, M.T.,Rossjohn, J.,Pulliainen, A.T.,Beddoe, T.,Littler, D.R.; Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.; J.Biol.Chem., 298:101892-101892, 2022; PubMed: 35378130; DOI: 10.1016/j.jbc.2022.101892

実験手法

X-RAY DIFFRACTION (1.09912437248 Å)