7SIA

HIV Integrase core domain in complex with inhibitor 2-[2-(2-{3-[(4-{2-[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)formamido]ethyl}piperazin-1-yl)methyl]phenyl}ethynyl)-5-methyl-1-benzofuran-3-yl]acetic acid

Summary for 7SIA

• Entry DOI: 10.2210/pdb7sia/pdb
• Related: 7RQ0
• Descriptor: Integrase, (2-{[3-({4-[2-(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzamido)ethyl]piperazin-1-yl}methyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid, IODIDE ION, ... (5 entities in total)
• Functional Keywords: inhibitor, hiv integrase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 37045.88

Authors

Gorman, M.A.,Parker, M.W. (deposition date: 2021-10-12, release date: 2022-10-19, Last modification date: 2023-10-18)

• Primary citation: Gorman, M.A.,Parker, M.W.; HIV Integrase core domain in complex with inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)