7SIA

HIV Integrase core domain in complex with inhibitor 2-[2-(2-{3-[(4-{2-[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)formamido]ethyl}piperazin-1-yl)methyl]phenyl}ethynyl)-5-methyl-1-benzofuran-3-yl]acetic acid

7SIA の概要

• エントリーDOI: 10.2210/pdb7sia/pdb
• 関連するPDBエントリー: 7RQ0
• 分子名称: Integrase, (2-{[3-({4-[2-(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzamido)ethyl]piperazin-1-yl}methyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid, IODIDE ION, ... (5 entities in total)
• 機能のキーワード: inhibitor, hiv integrase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Human immunodeficiency virus 1 (HIV-1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37045.88

構造登録者

Gorman, M.A.,Parker, M.W. (登録日: 2021-10-12, 公開日: 2022-10-19, 最終更新日: 2023-10-18)

• 主引用文献: Gorman, M.A.,Parker, M.W.; HIV Integrase core domain in complex with inhibitor; To Be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)