7SHU
IgE-Fc in complex with omalizumab variant C02
Summary for 7SHU
| Entry DOI | 10.2210/pdb7shu/pdb |
| Descriptor | omalizumab variant C02 VH, omalizumab variant C02 VL, Immunoglobulin heavy constant epsilon, ... (9 entities in total) |
| Functional Keywords | ige, omalizumab, xolair, inhibitor, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 6 |
| Total formula weight | 106919.03 |
| Authors | Pennington, L.F.,Jardetzky, T.J.,Kleinboelting, S. (deposition date: 2021-10-11, release date: 2021-12-15, Last modification date: 2023-10-18) |
| Primary citation | Pennington, L.F.,Gasser, P.,Kleinboelting, S.,Zhang, C.,Skiniotis, G.,Eggel, A.,Jardetzky, T.S. Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12:7069-7069, 2021 Cited by PubMed: 34862384DOI: 10.1038/s41467-021-27397-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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