7SHU

IgE-Fc in complex with omalizumab variant C02

7SHU の概要

• エントリーDOI: 10.2210/pdb7shu/pdb
• 分子名称: omalizumab variant C02 VH, omalizumab variant C02 VL, Immunoglobulin heavy constant epsilon, ... (9 entities in total)
• 機能のキーワード: ige, omalizumab, xolair, inhibitor, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 106919.03

構造登録者

Pennington, L.F.,Jardetzky, T.J.,Kleinboelting, S. (登録日: 2021-10-11, 公開日: 2021-12-15, 最終更新日: 2023-10-18)

• 主引用文献: Pennington, L.F.,Gasser, P.,Kleinboelting, S.,Zhang, C.,Skiniotis, G.,Eggel, A.,Jardetzky, T.S.; Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.; Nat Commun, 12:7069-7069, 2021; PubMed: 34862384; DOI: 10.1038/s41467-021-27397-z

実験手法

X-RAY DIFFRACTION (2.75 Å)