7SHB

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI79

7SHB の概要

• エントリーDOI: 10.2210/pdb7shb/pdb
• 分子名称: 3C-like proteinase nsp5, benzyl [(2S)-1-({(2S)-1-[2-(3-amino-3-oxopropyl)-2-propanoylhydrazinyl]-4-methyl-1-oxopentan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]carbamate (non-preferred name) (3 entities in total)
• 機能のキーワード: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34379.15

構造登録者

Yang, K.S.,Liu, W.R. (登録日: 2021-10-08, 公開日: 2024-07-10)

• 主引用文献: Yang, K.S.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)