7SH8

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI88

7SH8 の概要

• エントリーDOI: 10.2210/pdb7sh8/pdb
• 分子名称: 3C-like proteinase nsp5, benzyl [(2S,3R)-1-{[(2S)-1-(2-acetyl-2-{[(3S)-2-oxopyrrolidin-3-yl]methyl}hydrazinyl)-3-cyclohexyl-1-oxopropan-2-yl]amino}-3-tert-butoxy-1-oxobutan-2-yl]carbamate (non-preferred name) (3 entities in total)
• 機能のキーワード: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34489.31

構造登録者

Yang, K.S.,Liu, W.R. (登録日: 2021-10-08, 公開日: 2023-04-12, 最終更新日: 2023-11-15)

• 主引用文献: Yang, K.S.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)