7SH4

CD1a-phosphatidylglycerol binary structure

Summary for 7SH4

• Entry DOI: 10.2210/pdb7sh4/pdb
• Descriptor: T-cell surface glycoprotein CD1a, Beta-2-microglobulin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: cd1, antigen presentation, lipid, immune system, phospholipid
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 46554.40

Authors

Wegrecki, M.,Rossjohn, J. (deposition date: 2021-10-07, release date: 2022-10-05, Last modification date: 2023-10-25)

• Primary citation: Monnot, G.C.,Wegrecki, M.,Cheng, T.Y.,Chen, Y.L.,Sallee, B.N.,Chakravarthy, R.,Karantza, I.M.,Tin, S.Y.,Khaleel, A.E.,Monga, I.,Uwakwe, L.N.,Tillman, A.,Cheng, B.,Youssef, S.,Ng, S.W.,Shahine, A.,Garcia-Vilas, J.A.,Uhlemann, A.C.,Bordone, L.A.,Han, A.,Rohde, C.H.,Ogg, G.,Moody, D.B.,Rossjohn, J.,de Jong, A.; Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.; Nat.Immunol., 24:110-122, 2023; PubMed: 36550321; DOI: 10.1038/s41590-022-01375-z

Experimental method

X-RAY DIFFRACTION (2 Å)