7SG1

XPA5 TCR in complex with HLA-DQ2-alpha1

Summary for 7SG1

Entry DOI	10.2210/pdb7sg1/pdb
Descriptor	HLA class II histocompatibility antigen, DQ alpha 1 chain, MHC class II HLA-DQ-beta-1, T-cell receptor, xpa5, alpha chain, ... (8 entities in total)
Functional Keywords	tcr-pmhc, celiac disease, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	10
Total formula weight	194951.61
Authors	Ciacchi, L.,Farenc, C.,Petersen, J.,Reid, H.H.,Rossjohn, J. (deposition date: 2021-10-04, release date: 2022-02-23, Last modification date: 2023-10-18)
Primary citation	Ciacchi, L.,Farenc, C.,Dahal-Koirala, S.,Petersen, J.,Sollid, L.M.,Reid, H.H.,Rossjohn, J. Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease. J.Biol.Chem., 298:101619-101619, 2022 Cited by PubMed: 35065967 DOI: 10.1016/j.jbc.2022.101619 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation