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7SF5

M. tb EgtD in complex with HD3

Summary for 7SF5
Entry DOI10.2210/pdb7sf5/pdb
DescriptorHistidine N-alpha-methyltransferase, N-(benzylcarbamothioyl)-L-histidine (3 entities in total)
Functional Keywordssam dependent methyl transferase, peptide like inhibitor, sam binding domain, histidine binding domain, transferase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains2
Total formula weight71238.31
Authors
Sudasinghe, T.D.,Ronning, D.R. (deposition date: 2021-10-03, release date: 2021-12-01, Last modification date: 2023-10-18)
Primary citationSudasinghe, T.D.,Banco, M.T.,Ronning, D.R.
Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production.
Sci Rep, 11:22240-22240, 2021
Cited by
PubMed: 34782676
DOI: 10.1038/s41598-021-01526-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.52 Å)
Structure validation

221716

數據於2024-06-26公開中

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