7SF5
M. tb EgtD in complex with HD3
Summary for 7SF5
Entry DOI | 10.2210/pdb7sf5/pdb |
Descriptor | Histidine N-alpha-methyltransferase, N-(benzylcarbamothioyl)-L-histidine (3 entities in total) |
Functional Keywords | sam dependent methyl transferase, peptide like inhibitor, sam binding domain, histidine binding domain, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 71238.31 |
Authors | Sudasinghe, T.D.,Ronning, D.R. (deposition date: 2021-10-03, release date: 2021-12-01, Last modification date: 2023-10-18) |
Primary citation | Sudasinghe, T.D.,Banco, M.T.,Ronning, D.R. Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production. Sci Rep, 11:22240-22240, 2021 Cited by PubMed: 34782676DOI: 10.1038/s41598-021-01526-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
Download full validation report