7SCP

The crystal structure of ScoE in complex with intermediate

Summary for 7SCP

• Entry DOI: 10.2210/pdb7scp/pdb
• Descriptor: ScoE protein, FE (II) ION, (3R)-3-(oxaloamino)butanoic acid, ... (6 entities in total)
• Functional Keywords: iron/2-oxoglutarate dependent, fe/2og, isonitrile biosynthesis, biosynthetic protein
• Biological source: Streptomyces coeruleorubidus
• Total number of polymer chains: 1
• Total formula weight: 40307.76

Authors

Cha, L.,Chen, J.,Zhou, J.,Chang, W. (deposition date: 2021-09-28, release date: 2022-03-23, Last modification date: 2023-10-18)

• Primary citation: Chen, T.Y.,Zheng, Z.,Zhang, X.,Chen, J.,Cha, L.,Tang, Y.,Guo, Y.,Zhou, J.,Wang, B.,Liu, H.W.,Chang, W.C.; Deciphering the Reaction Pathway of Mononuclear Iron Enzyme-Catalyzed N-C Triple Bond Formation in Isocyanide Lipopeptide and Polyketide Biosynthesis; Acs Catalysis, 12:2270-2279, 2022; DOI: 10.1021/acscatal.1c04869

Experimental method

X-RAY DIFFRACTION (1.99 Å)