7SBM
Human glutaminase C (Y466W) with L-Gln, open conformation
Summary for 7SBM
Entry DOI | 10.2210/pdb7sbm/pdb |
Descriptor | Isoform 3 of Glutaminase kidney isoform, mitochondrial, GLUTAMINE (3 entities in total) |
Functional Keywords | complex, oligomer, cancer metabolism, mitochondrial metabolism, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 238507.09 |
Authors | Nguyen, T.-T.T.,Cerione, R.A. (deposition date: 2021-09-25, release date: 2022-02-02, Last modification date: 2023-10-18) |
Primary citation | Nguyen, T.T.,Ramachandran, S.,Hill, M.J.,Cerione, R.A. High-resolution structures of mitochondrial glutaminase C tetramers indicate conformational changes upon phosphate binding. J.Biol.Chem., 298:101564-101564, 2022 Cited by PubMed: 34999118DOI: 10.1016/j.jbc.2022.101564 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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