7SB6
Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2
Summary for 7SB6
Entry DOI | 10.2210/pdb7sb6/pdb |
Descriptor | Cadherin 23, CALCIUM ION, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | hearing, mechanotransduction, adhesion, calcium-binding protein, cell adhesion, evolution |
Biological source | synthetic construct |
Total number of polymer chains | 3 |
Total formula weight | 72144.65 |
Authors | Nisler, C.R.,Narui, Y.,Sotomayor, M. (deposition date: 2021-09-23, release date: 2022-10-05, Last modification date: 2023-10-25) |
Primary citation | Nisler, C.R.,Narui, Y.,Scheib, E.,Choudhary, D.,Bowman, J.D.,Mandayam Bharathi, H.,Lynch, V.J.,Sotomayor, M. Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40:-, 2023 Cited by PubMed: 36911992DOI: 10.1093/molbev/msad057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.588 Å) |
Structure validation
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