7SA9

Human MUC16 SEA5 Domain

Summary for 7SA9

• Entry DOI: 10.2210/pdb7sa9/pdb
• Descriptor: Mucin-16 (2 entities in total)
• Functional Keywords: mucin, ca125, ovarian cancer, pancreatic cancer, unknown function
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 41434.36

Authors

Brooks, C.L.,White, B. (deposition date: 2021-09-22, release date: 2022-03-23, Last modification date: 2023-10-18)

• Primary citation: White, B.,Patterson, M.,Karnwal, S.,Brooks, C.L.; Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor marker.; Proteins, 90:1210-1218, 2022; PubMed: 35037700; DOI: 10.1002/prot.26303

Experimental method

X-RAY DIFFRACTION (1.69 Å)