7S9O
Binary complex of DNA Polymerase Beta with Ring open Intermediate Fapy-dG in the template position
Summary for 7S9O
Entry DOI | 10.2210/pdb7s9o/pdb |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*C*(IFP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A*(SO4))-3'), ... (6 entities in total) |
Functional Keywords | fapy-dg intermediate, polymerase beta, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 47795.88 |
Authors | Freudenthal, B.D.,Ryan, B.J. (deposition date: 2021-09-21, release date: 2022-08-03, Last modification date: 2023-10-18) |
Primary citation | Ryan, B.J.,Yang, H.,Bacurio, J.H.T.,Smith, M.R.,Basu, A.K.,Greenberg, M.M.,Freudenthal, B.D. Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication. J.Am.Chem.Soc., 144:8054-8065, 2022 Cited by PubMed: 35499923DOI: 10.1021/jacs.2c00193 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
Download full validation report