7S8G

Structure of anti-LASV Fab 25.10C with FNQI mutation

Summary for 7S8G

Entry DOI	10.2210/pdb7s8g/pdb
Descriptor	25.10C-FNQI Fab Heavy Chain, 25.10C-FNQI Fab Light Chain (3 entities in total)
Functional Keywords	anti-lasv fab, elbow mutation, domain swap, antiviral protein, immune system
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	95012.23
Authors	Hastie, K.M.,Enriquez, A.S. (deposition date: 2021-09-17, release date: 2022-06-01, Last modification date: 2023-10-18)
Primary citation	Enriquez, A.S.,Buck, T.K.,Li, H.,Norris, M.J.,Moon-Walker, A.,Zandonatti, M.A.,Harkins, S.S.,Robinson, J.E.,Branco, L.M.,Garry, R.F.,Saphire, E.O.,Hastie, K.M. Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies. Cell Rep, 39:110841-110841, 2022 Cited by PubMed: 35613585 DOI: 10.1016/j.celrep.2022.110841 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.57 Å)

Structure validation