7S2M
Crystal structure of sulfonamide resistance enzyme Sul3 in complex with 6-hydroxymethylpterin
Summary for 7S2M
Entry DOI | 10.2210/pdb7s2m/pdb |
Related | 7S2L 7S2O |
Descriptor | Sul3, 6-HYDROXYMETHYLPTERIN (3 entities in total) |
Functional Keywords | tim barrel, alpha beta protein, antibiotic resistance, sulfonamides, structural genomics, csgid, center for structural genomics of infectious diseases, niaid, national institute of allergy and infectious diseases, transferase |
Biological source | uncultured bacterium |
Total number of polymer chains | 3 |
Total formula weight | 87938.18 |
Authors | Stogios, P.J.,Skarina, T.,Venkatesan, M.,Michalska, K.,Mesa, N.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Biology of Infectious Diseases (CSBID),Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-09-03, release date: 2023-05-03, Last modification date: 2023-10-25) |
Primary citation | Venkatesan, M.,Fruci, M.,Verellen, L.A.,Skarina, T.,Mesa, N.,Flick, R.,Pham, C.,Mahadevan, R.,Stogios, P.J.,Savchenko, A. Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics. Nat Commun, 14:4031-4031, 2023 Cited by PubMed: 37419898DOI: 10.1038/s41467-023-39778-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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