7S17
Crystal structure of human G3BP1-NTF2 with three mutations- F15W, F33W, and F124W
Summary for 7S17
Entry DOI | 10.2210/pdb7s17/pdb |
Related | 4FCJ |
Descriptor | Ras GTPase-activating protein-binding protein 1 (2 entities in total) |
Functional Keywords | ntf2-like domain, binding mutant, rna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 32092.42 |
Authors | Sheehan, C.T.,Madden, D.R. (deposition date: 2021-09-01, release date: 2022-10-12, Last modification date: 2023-10-25) |
Primary citation | Sheehan, C.T.,Hampton, T.H.,Madden, D.R. Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10. J.Biol.Chem., 298:102552-102552, 2022 Cited by PubMed: 36183834DOI: 10.1016/j.jbc.2022.102552 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
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